Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep779 | Obesity | ECE2016

Skin autofluorescence is associated with the metabolic syndrome and its individual components

van Waateringe Robert , Slagter Sandra , van Vliet-Ostaptchouck Jana , Graaff Reindert , van der Klauw Melanie , Paterson Andrew , Lutgers Helen , Wolffenbuttel Bruce

Background: Skin autofluorescence (SAF) has been demonstrated to be associated with long-term cardiovascular complications in subjects with either diabetes or renal failure. Since the metabolic syndrome (MetS) is a risk factor for cardiovascular disease, the aim of the study was to assess the association between SAF and MetS as well as its individuals components.Materials and methods: For this cross-sectional analysis, we included subjects 18–80 yea...

ea0056gp247 | Thyroid non cancer | ECE2018

Serum FT4 levels predict incidence of type 2 diabetes and cardiovascular disease in the general population

Wolffenbuttel Bruce HR , van Vliet-Ostaptchouk Jana V , van Waateringe Robert P , Wouters Hanneke JCM. , Slagter Sandra N , Graaff Reindert , van der Klauw Melanie M

Background: Skin autofluorescence (SAF), measured with the AGE-reader, predicts cardiovascular disease (CVD) and type 2 diabetes (T2D). Thyroid hormone levels (TH) may affect this association. In the present study, we examined whether TH predict 4-years risk of T2D, CVD and mortality in the general population independently of SAF.Methods: We included 28245 participants (age 44±12 years, BMI 25.9±4.3 kg/m2) of the Dutch Lifelines Coho...